Model Card for Mistral-Codon-v1-1M (Mistral for coding DNA)

The Mistral-Codon-v1-1M Large Language Model (LLM) is a pretrained generative DNA sequence model with 1M parameters. It is derived from Mixtral-8x7B-v0.1 model, which was simplified for DNA: the number of layers and the hidden size were reduced. The model was pretrained using 24M coding DNA sequences (3000bp) from many different species (vertebrates, plants, bacteria, viruses, ...).

Model Architecture

Like Mixtral-8x7B-v0.1, it is a transformer model, with the following architecture choices:

• Grouped-Query Attention
• Sliding-Window Attention
• Byte-fallback BPE tokenizer
• Mixture of Experts

Load the model from huggingface:

import torch
from transformers import AutoTokenizer, AutoModel

tokenizer = AutoTokenizer.from_pretrained("RaphaelMourad/Mistral-Codon-v1-1M", trust_remote_code=True) 
model = AutoModel.from_pretrained("RaphaelMourad/Mistral-Codon-v1-1M", trust_remote_code=True)

Calculate the embedding of a coding sequence

codon_dna = "TGA TGA TTG GCG CGG CTA GGA TCG GCT"
inputs = tokenizer(codon_dna, return_tensors = 'pt')["input_ids"]
hidden_states = model(inputs)[0] # [1, sequence_length, 256]

# embedding with max pooling
embedding_max = torch.max(hidden_states[0], dim=0)[0]
print(embedding_max.shape) # expect to be 256

Troubleshooting

Ensure you are utilizing a stable version of Transformers, 4.34.0 or newer.

Notice

Mistral-Codon-v1-1M is a pretrained base model for coding DNA.

Contact

Raphaël Mourad. raphael.mourad@univ-tlse3.fr